Effect of early long-pulse pulsed dye laser treatment in infantile hemangiomas

SH Kwon, JW Choi, SY Byun, BR Kim… - Dermatologic …, 2014 - journals.lww.com
SH Kwon, JW Choi, SY Byun, BR Kim, KC Park, SW Youn, CH Huh, J Im Na
Dermatologic Surgery, 2014journals.lww.com
BACKGROUND Despite several recent reports on the efficacy of long-pulse pulsed dye
laser (LP-PDL) in treating infantile hemangiomas, controversy remains. OBJECTIVES To
determine the beneficial effects of early therapeutic intervention with LP-PDL in superficial
and mixed hemangiomas. METHODS AND MATERIALS Clinical data from 40 children with
47 hemangiomas in preproliferative or proliferative phase treated with LP-PDL in a Korean
tertiary hospital over 5 years were analyzed retrospectively. Treatments were repeated at 1 …
BACKGROUND Despite several recent reports on the efficacy of long-pulse pulsed dye laser (LP-PDL) in treating infantile hemangiomas, controversy remains.
OBJECTIVES To determine the beneficial effects of early therapeutic intervention with LP-PDL in superficial and mixed hemangiomas.
METHODS AND MATERIALS Clinical data from 40 children with 47 hemangiomas in preproliferative or proliferative phase treated with LP-PDL in a Korean tertiary hospital over 5 years were analyzed retrospectively. Treatments were repeated at 1-to 4-week intervals until growth stopped.
RESULTS Of the 47 hemangiomas, 32 were superficial, and 15 were mixed at presentation. Age was 9.6±5.9 weeks at initiation of treatment and 18.0±8.6 weeks at completion, and a positive linear correlation existed between the two. There were a mean of 4.6±2.6 treatments per hemangioma, which was lower in superficial than in mixed hemangiomas. Improvement in color was documented in 84.4% of superficial and 86.7% of mixed hemangiomas, and 75.0% of superficial and 66.7% of mixed shrank. Hyperpigmentation occurred in two superficial hemangiomas.
CONCLUSION Early intervention in hemangiomas using LP-PDL successfully prevents further growth and accelerates a transition to plateau or involution phase with minimal adverse events, achieving good cosmetic outcomes.
Lippincott Williams & Wilkins