Background Tissue-resident memory T (T RM) cells are known to be important for the first
line of defense in mucosa-associated tissues. However, the composition, localization,
effector function, and specificity of T RM cells in the human kidney and their relevance for
renal pathology have not been investigated. Methods Lymphocytes derived from blood,
renal peritumor samples, and tumor samples were phenotypically and functionally assessed
by applying flow cytometry and highly advanced histology (multi-epitope ligand cartography) …