Lipid droplets are accumulations of neutral lipids surrounded by a monolayer of
phospholipids and associated proteins. Recent proteomic analysis of isolated droplets
suggests that they are part of a dynamic organelle system that is involved in membrane
traffic as well as packaging and distributing lipids in the cell. To gain a better insight into the
function of droplets, we used a combination of mass spectrometry and NMR spectroscopy to
characterize the lipid composition of this compartment. In addition to cholesteryl esters and …