pLogo: a probabilistic approach to visualizing sequence motifs
JP O'shea, MF Chou, SA Quader, JK Ryan… - Nature …, 2013 - nature.com
Nature methods, 2013•nature.com
Methods for visualizing protein or nucleic acid motifs have traditionally relied upon residue
frequencies to graphically scale character heights. We describe the pLogo, a motif
visualization in which residue heights are scaled relative to their statistical significance. A
pLogo generation tool is publicly available at http://plogo. uconn. edu/and supports real-time
conditional probability calculations and visualizations.
frequencies to graphically scale character heights. We describe the pLogo, a motif
visualization in which residue heights are scaled relative to their statistical significance. A
pLogo generation tool is publicly available at http://plogo. uconn. edu/and supports real-time
conditional probability calculations and visualizations.
Abstract
Methods for visualizing protein or nucleic acid motifs have traditionally relied upon residue frequencies to graphically scale character heights. We describe the pLogo, a motif visualization in which residue heights are scaled relative to their statistical significance. A pLogo generation tool is publicly available at http://plogo.uconn.edu/ and supports real-time conditional probability calculations and visualizations.
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