[HTML][HTML] Phospholipase A2 structure/function, mechanism, and signaling1
JE Burke, EA Dennis - Journal of lipid research, 2009 - ASBMB
Tremendous advances in understanding the structure and function of the superfamily of
phospholipase A 2 (PLA 2) enzymes has occurred in the twenty-first century. The
superfamily includes 15 groups comprising four main types including the secreted sPLA 2,
cytosolic cPLA 2, calcium-independent iPLA 2, and platelet activating factor (PAF) acetyl
hydrolase/oxidized lipid lipoprotein associated (Lp) PLA 2. We review herein our current
understanding of the structure and interaction with substrate phospholipids, which resides in …
phospholipase A 2 (PLA 2) enzymes has occurred in the twenty-first century. The
superfamily includes 15 groups comprising four main types including the secreted sPLA 2,
cytosolic cPLA 2, calcium-independent iPLA 2, and platelet activating factor (PAF) acetyl
hydrolase/oxidized lipid lipoprotein associated (Lp) PLA 2. We review herein our current
understanding of the structure and interaction with substrate phospholipids, which resides in …