[HTML][HTML] T‐cell‐derived cytokines enhance the antigen‐presenting capacity of human neutrophils

N Samadi, D Polak, C Kitzmüller… - European Journal of …, 2019 - ncbi.nlm.nih.gov
N Samadi, D Polak, C Kitzmüller, P Steinberger, GJ Zlabinger, B Jahn‐Schmid, B Bohle
European Journal of Immunology, 2019ncbi.nlm.nih.gov
Activated allergen‐specific Th2 and Th1 cells release cytokines that transform neutrophils
into functional APCs characterized by the expression of HLA‐DR and CD58 as well as
enhanced survival and antigen uptake, irrespectively of the presence of IL‐10, which
reduces allergen uptake by neutrophils.
Abstract
Activated allergen‐specific Th2 and Th1 cells release cytokines that transform neutrophils into functional APCs characterized by the expression of HLA‐DR and CD58 as well as enhanced survival and antigen uptake, irrespectively of the presence of IL‐10, which reduces allergen uptake by neutrophils.
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