Fatal varicella associated with selective natural killer cell deficiency
A Etzioni, C Eidenschenk, R Katz, R Beck… - The Journal of …, 2005 - Elsevier
The Journal of pediatrics, 2005•Elsevier
A 2-year-old girl with recurrent severe varicella infections had a fatal outcome. Studies of
cellular and humoral immunity were normal. No natural killer (NK) cells were detected, and
NK activity was markedly decreased. The interleukin (IL) 15/IL15R signaling pathway was
intact. This case emphasizes the role of NK cells in controlling herpes viral infection.
cellular and humoral immunity were normal. No natural killer (NK) cells were detected, and
NK activity was markedly decreased. The interleukin (IL) 15/IL15R signaling pathway was
intact. This case emphasizes the role of NK cells in controlling herpes viral infection.
A 2-year-old girl with recurrent severe varicella infections had a fatal outcome. Studies of cellular and humoral immunity were normal. No natural killer (NK) cells were detected, and NK activity was markedly decreased. The interleukin (IL)15/IL15R signaling pathway was intact. This case emphasizes the role of NK cells in controlling herpes viral infection.
Elsevier