Emerging role of Notch in stem cells and cancer
Z Wang, Y Li, S Banerjee, FH Sarkar - Cancer letters, 2009 - Elsevier
Z Wang, Y Li, S Banerjee, FH Sarkar
Cancer letters, 2009•ElsevierThe Notch signaling pathway is known to be responsible for maintaining a balance between
cell proliferation and death and, as such, plays important roles in the formation of many
types of human tumors. Recently, Notch signaling pathway has been shown to control stem
cell self-renewal and multi-potency. As many cancers are thought to be developed from a
number of cancer stem-like cells, which are also known to be linked with the acquisition of
epithelial-mesenchymal transition (EMT); and thus suggesting an expanding role of Notch …
cell proliferation and death and, as such, plays important roles in the formation of many
types of human tumors. Recently, Notch signaling pathway has been shown to control stem
cell self-renewal and multi-potency. As many cancers are thought to be developed from a
number of cancer stem-like cells, which are also known to be linked with the acquisition of
epithelial-mesenchymal transition (EMT); and thus suggesting an expanding role of Notch …
The Notch signaling pathway is known to be responsible for maintaining a balance between cell proliferation and death and, as such, plays important roles in the formation of many types of human tumors. Recently, Notch signaling pathway has been shown to control stem cell self-renewal and multi-potency. As many cancers are thought to be developed from a number of cancer stem-like cells, which are also known to be linked with the acquisition of epithelial-mesenchymal transition (EMT); and thus suggesting an expanding role of Notch signaling in human tumor progression.
Elsevier