Post–transcriptional control of gene expression during spermatogenesis
RE Braun - Seminars in cell & developmental biology, 1998 - Elsevier
RE Braun
Seminars in cell & developmental biology, 1998•ElsevierThe synthesis and storage of mRNAs prior to their translation is a necessity during
spermatogenesis as global transcription ceases several days prior to the completion of
spermatid differentiation. Post–transcriptional control can be mediated by sequences in the
5′ and 3′ untranslated regions of mRNAs, and in some cases separate elements may
regulate translational repression and translational activation. Translational repression is
essential for spermatid differentiation as premature translation can lead to an arrest in …
spermatogenesis as global transcription ceases several days prior to the completion of
spermatid differentiation. Post–transcriptional control can be mediated by sequences in the
5′ and 3′ untranslated regions of mRNAs, and in some cases separate elements may
regulate translational repression and translational activation. Translational repression is
essential for spermatid differentiation as premature translation can lead to an arrest in …
The synthesis and storage of mRNAs prior to their translation is a necessity during spermatogenesis as global transcription ceases several days prior to the completion of spermatid differentiation. Post–transcriptional control can be mediated by sequences in the 5′ and 3′ untranslated regions of mRNAs, and in some cases separate elements may regulate translational repression and translational activation. Translational repression is essential for spermatid differentiation as premature translation can lead to an arrest in spermatid differentiation and cause dominant male sterility.
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