Phenotype and function of myeloid dendritic cells derived from African green monkey blood monocytes
L Mortara, MJY Ploquin, A Faye, D Scott-Algara… - Journal of …, 2006 - Elsevier
Myeloid dendritic cells probably play an important role in the immune response against HIV
and SIV, and in the enhancement of CD4+ T cell infection. Here, we have investigated
phenotypic and functional features of myeloid monocyte-derived DC (MDDC) from African
green monkeys (AGMs). AGMs are natural hosts of SIV and exhibit no signs of abnormal T
cell activation despite high SIV plasma viremia. We identified mAbs that cross-react
specifically with homologous molecules expressed on AGM DC. We adapted a protocol to …
and SIV, and in the enhancement of CD4+ T cell infection. Here, we have investigated
phenotypic and functional features of myeloid monocyte-derived DC (MDDC) from African
green monkeys (AGMs). AGMs are natural hosts of SIV and exhibit no signs of abnormal T
cell activation despite high SIV plasma viremia. We identified mAbs that cross-react
specifically with homologous molecules expressed on AGM DC. We adapted a protocol to …
